
Clinically isolated syndrome (CIS) - Multiple Sclerosis News Today
Dec 18, 2025 · Several factors may affect CIS prognosis and the likelihood of developing MS. Notably, the chances of developing MS are greater in people with brain lesions at the time of their CIS …
Clinically Isolated Syndrome (CIS) | National MS Society
Clinically Isolated Syndrome (CIS) is a first episode of symptoms that may develop into MS. Discover information & resources to help navigate a CIS diagnosis.
Multiple sclerosis development: what is clinically isolated syndrome (CIS…
Clinically isolated syndrome (CIS) is often a sign of multiple sclerosis and the term refers to the first episode of neurologic symptoms experienced by a patient.
Clinically Isolated Syndrome (CIS) Treatment Options in 2025: What’s ...
Sep 8, 2025 · People at high risk after CIS sometimes start treatment via private funding or clinical trials. Talk to your neurologist early about pathways. Use this as a practical, no-drama workflow. Confirm …
Clinically Isolated Syndromes: Clinical Characteristics, Differential ...
Patients with CIS (and abnormal MRI scans) are at a high risk of developing CDMS (18). Hence, when an individual presents with CIS, the challenge for the clinician is to determine the likelihood of the …
Clinically Isolated Syndrome - Cedars-Sinai
The FDA has approved medications to manage the symptoms of certain types of MS and patients diagnosed with high-risk CIS may be prescribed one or more of these to delay the onset of MS and …
Clinically Isolated Syndrome (CIS) Diagnosis
A Clinically Isolated Syndrome (CIS) diagnosis can be an early sign of MS, but not for everyone. Find out what the cause is, symptoms & treatments for CIS.
Multiple Sclerosis Foundation - Clinically Isolated Syndrome
How CIS presents clinically may give us some clues as to whether there is a higher risk for the development of MS. In transverse myelitis, milder symptoms (i.e. numbness without weakness) are …
Clinically Isolated Demyelinating Syndromes - Northwestern Medicine
Clinically isolated syndrome (CIS) describes a single attack of symptoms that are like those of multiple sclerosis. An MRI scan of a patient who experienced CIS can help determine whether they are at low …
Clinically isolated syndrome: Diagnosis and risk of developing ...
Nov 1, 2023 · Codetection of oligoclonal IgG bands and MRI lesions reduces diagnostic delays and suggests a high risk of CIS progression to MS.