These parts of the selectin molecules are responsible for their targeting to different compartments: P-selectin to secretory granules, E-selectin to the plasma membrane, and L-selectin to the tips of …

Aug 2, 2025 · L-selectin is found on leukocytes, enabling their interactions within the bloodstream. E-selectin is expressed on endothelial cells, especially during inflammatory responses.

This review summarizes selectin biology and pathology, structure and ligand binding, and selectin antagonists that have reached clinical testing with an emphasis on E-selectin.

This page covers selectins, a group of cell adhesion molecules that bind to specific oligosaccharides on glycoproteins. The main types are L-selectin, E-selectin, and P-selectin, each important for …

selectin noun se· lec· tin sə-ˈlek-tin : any of various sugar-binding proteins found on the surface of cells that are involved in the calcium-dependent adhesion of cells (such as white blood cells) to other cells …

Three selectins (P-selectin, E-selectin, and L-selectin) have been identified, each differing in their patterns of expression and regulation.

Jul 19, 2023 · Three type-I-cell surface glycoproteins make up the selectin family, namely L-selectin, P-selectin and E-selectin.

Apr 20, 2025 · The selectin family consists of three main types: E-selectin (expressed on endothelial cells), P-selectin (found on platelets and endothelial cells), and L-selectin (present on leukocytes). …

There are three types of selectins: L-selectin (CD62L), E-selectin (CD62E), and P-selectin (CD62P), each with a specific expression pattern and binding preference.

Aug 22, 2025 · Selectin-mediated rolling adhesion is a first step in the body’s defense mechanisms, especially during inflammation. When tissues are infected or injured, endothelial cells lining nearby …